How Type 2 Diabetes Occurs

Extra weight, inflammation, and insulin resistance is a likely path to type 2. Here's how those at risk can prevent a diagnosis.


Being overweight is a health gamble--especially because those extra pounds can lead to a diagnosis of pre-diabetes and eventually type 2 diabetes.

"As more Americans gain weight, they risk triggering a cascade of events involving insulin resistance and inflammation that rolls the dice in favor of type 2 diabetes," says Peter Sheehan, M.D., of Mount Sinai School of Medicine in New York City and chair of the Cardiometabolic Risk Subcommittee for the American Diabetes Association (ADA).

The good news? You and your at-risk family members may be able to head off the disease through weight loss, healthful eating, and physical activity.